A regimen of berberine/red yeast rice/astaxanthin might constitute a safe and usually well-tolerated strategy for optimising lipid profiles in patients in whom triglycerides and LDL cholesterol are both elevated, and HDL cholesterol depressed.
Meta-analysis confirms the utility of krill oil supplementation for improving serum lipid profile.Its efficacy with respect to modulating serum lipids, glucose and C reactive protein appears to be superior to that of fish oil.
Reference: https://openheart.bmj.com/content/openhrt/6/2/e000977.full.pdf