Tag Archives: longevity

Dosage, Formulas, Supplements

NAD + Pterostilbene Anti Aging, Mimic Calorie Restriction Effects

NAD + Pterostilbene formula expected to mimic calorie restriction anti aging effects:

A synergistic anti aging effect is expected from combining Nicotinamide Riboside and Pterostilbene.

Nicotinamide riboside represents an innovative advance to combat aging that functions via unique mechanisms not found in typical dietary supplements.
Nicotinamide riboside has been documented to help replenish cellular NAD+.

Benefits:

  • Longevity: NR increases the amount of NAD in the body, which can help reprogram dysfunctional cells. These combined effects can help increase longevity in mammals.  NR induced the mitochondrial unfolded protein response and synthesis of prohibiting proteins, and this rejuvenated stem cells in aged mice.
  • Mitochondria: The nucleus and mitochondria can both metabolise NR.  Its supplementation raises the nuclear and mitochondrial NAD+ levels, thereby activating nuclear SIRT1 and mitochondrial SIRT3 respectively.
    Enhance growth and efficiency of mitochondria, supporting energy levels and physical performance,
  • Nootropic: Contribute to neuronal health, supporting cognitive function during aging. Proper NAD metabolism can help protect the brain. NR protects the nerve cells in the brain by activating the SIRT3 and PGC1a pathways.
  • Glucose tolerance: Promote insulin sensitivity, supporting healthy blood sugar levels in those within the normal range.

Pterostilbene is similar in structure to the anti-aging compound resveratrol, but is more bioavailable and preliminary research indicates that in some ways, it may be even more beneficial. Preliminary research shows that pterostilbene may help with healthy cognitive function and may support glucose levels already in a normal range. Emerging science indicates that it may also help support healthy blood lipid levels and a healthy inflammation response.

Reference:

https://www.technologyreview.com/s/534636/the-anti-aging-pill
https://medcom.uiowa.edu/theloop/news/first-human-clinical-trial-for-nicotinamide-riboside

What Is Nicotinamide Riboside? NAD+ Booster Benefits?


https://selfhacked.com/2016/08/29/nicotinamide-riboside/


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Formulas, Supplements

Ray Kurzweil Supplements List

The Google exec, futurist, author, and inventor is currently the search engine giant’s director of engineering and is working on an artificial intelligence initiative.

In an interview with MacLeans, Kurzweil asserted that “outdated software” is running our bodies, and needs to be reprogrammed to increase life expectancy. “Life expectancy was 20 a thousand years ago; 37, 200 years ago. We’re now able to reprogram health and medicine as software, and that [pace is] going to continue to accelerate.”

List of 77 supplements that Ray Kurzweil reports taking in his coauthored book, Fantastic Voyage: Live Long Enough to Live Forever

For anti-oxidation and general health

Comprehensive multi-vitamin
Coenzyme Q10
Grapeseed extract
Resveratrol
Bilberry extract
Lycopene
Silymarine
Linoleic acid
Lecithin
n-acetyl-cystein
Garlic
l-carnitine
Pyrodoxal-5-phosphate:
Echinacea
Herbs prescribed by Dr. Glenn Rothfeld
B12 shots

For treating type 2 diabates

Chromium
Metformine
Gymnema sylvestra

For Cholesterol levels

Policosanol
Gugulipid
Plant sterols
Niacin
Oat bran
Grapefruit powder
Psyllium
Lecithine
Lipitor

For blood-vessel health

Arginine
TMG
Choline

To lower blood viscosity

Aspirin
Lumbrokinase

To reduce inflammation

EPA/DHA
Curcumin

To reduce homocystein levels

Folic acid
B6

For detoxification

EDTA
DMPS

For the Liver

Intravenous glutathione

For cell membranes

Intravenous phosphatidylcholine

For testosterone levels

PtC
DHEA
Testosterone
l-3-C
Chrysin
Nettle
Ginger

For the prostate

Saw palmetto complex

For stress

l-theonine
Beta-sitosterol
Phosphatidylserine
Green tea extract

For the brain

GABA
Melatonin
Glycerylphosphatidylcholine
Nextrutine
Quercertin

For the eyes

Lutein
Bilberry extract

For the skin

Antioxidant skin creams

For digestion

Betaine HCL
Pepsin
Gentian root
Peppermint
Acidophilus bifodobacter
Fructooligosaccharides
Fish proteins
l-glutamine
n-acetyl-d-glucosamine

To inhibit glycolsylated end products

n-acetyl-carnitine
Carnosine
Quercertin
Alpha lipoic acid

Read more…


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